Aomatase inhibitor induced arthralgia

Drs Martin & Sue Allbright

'Blending an ancient medical approach of mind and body with modern health'

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Acupuncture Research

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Structure

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Evidence

We would like to share with you our personal view, beliefs and approach about the research that is presented on these pages.






We both value the research of modern science and the many developments that have been discovered.

We also value the depth of wisdom and knowledge of traditional and classical five element acupuncture, which integrates the many aspects of body and mind.

We acknowledge the information gained from research, and we endevaour to use it where appropriate when meeting the needs of an individual who is suffering in health.

We hope later to share more information on the five elements of acupuncture.

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Classical Acupuncture

This site was last updated on

10th March 2018


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Aromatase inhibitor-induced arthralgia (AIA) in patients with breast cancer

(2017) Effect of acupuncture on aromatase inhibitor-induced arthralgia in patients with breast cancer: A meta-analysis of randomized controlled trials

‘Results. Five trials involving 181 patients were reviewed. Significant pain reduction was observed after 6–8 weeks of acupuncture treatment. Patients receiving acupuncture showed a significant decrease in the Brief Pain Inventory (BPI) worst pain score (weighted mean difference [WMD]: −3.81, 95% confidence interval [CI]: −5.15 to −2.47) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain score (WMD: −130.77, 95% CI: −230.31 to −31.22) after 6–8 weeks of treatment.

Conclusion. Acupuncture is a safe and viable nonpharmacologic treatment that may relieve joint pain in patients with AIA. Additional studies involving a higher number of RCTs are warranted.'

Chen L. et al. (2017) Effect of acupuncture on aromatase inhibitor-induced arthralgia in patients with breast cancer: A meta-analysis of randomized controlled trials. The Breast Volume 33, June 2017, Pages 132–138


(2014) A randomised trial of electro-acupuncture (EA) for arthralgia related to aromatase inhibitor (Als) use.

'Compared to usual care, EA produced clinically important and durable improvement in arthralgia related to AIs in breast cancer patients, and Sham Acupuncture had a similar effect. Both EA and SA were safe.'

Jun J.Mao, Sharon X.Xie, John T.Farrar et al., (2014) A randomised trial of electro-acupuncture for arthralgia related to aromatase inhibitor use. European Journal of Cancer Volume 50, Issue 2, January 2014, Pages 267-276


(2014) Electroacupuncture (EA) for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia: A randomized trial


CONCLUSIONS: Compared with usual care, EA produced significant improvements in fatigue, anxiety, and depression; whereas Sham Acupuncture improved only depression in women experiencing AI-related arthralgia.

Mao, J. J., Farrar, J. T., Bruner, D., Zee, J., Bowman, M., Seluzicki, C., DeMichele, A. and Xie, S. X. (2014), Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia: A randomized trial. Cancer, 120: 3744–3751. doi:10.1002/cncr.28917

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Aromatase Oestrogen  synthase enzyme  molecule